Gut X · Liquid-First Delivery

Nutrition starts in the gut.
Liquid delivery makes it work.

Digestive ComfortImmune SupportBody Condition Support

Gut X is delivered in a proprietary liquid form with up to 99% availability1, 2. Powders & pellets must first break apart, hydrate, & disperse into usable surface area inside a moving gut, a slow, variable process that leaves availability as low as 2.5%3.

Gut X arrives dispersed, at the correct particle size, suspended and ready on contact, so the gut isn’t left to solve dispersion problems it was never designed to solve.

1Goodridge et al. (2011). doi.org/10.1038/nature100712Balogh et al. (2008). doi.org/10.1021/jf80170293Du et al. (2004). doi.org/10.1002/bdd.392
★★★★★ 4.9 / 5 15,921 reviews 112,000+ horses on product
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Your 2 Gallon Subscription includes
  • 2 Gallons of Gut X + 2 pumps
  • Free ½ gallon of Gut X ($89.95 value) *New Subscription Offer Only
  • $20,000 Colic Care Coverage Program
Gut X · 2 Gallon
112,000+Horses supported
USEF / FEIShow compliant
FREE SHIPPINGSame day, ship by 3pm CST
$20,000Colic coverage
Customer reviews

15,921 verified reviews from working barns.

Every discipline. Every level. Real horses on Dr. Peterson’s Protocol.

4.9
★★★★★
out of 5
Based on 15,921 verified reviews
5 stars
87%
4 stars
9%
3 stars
2%
2 stars
1%
1 stars
1%
Real Gut X Stories

Real Horses. Real Change.

The owners who watched it happen, in their own words.

Rev · Off-track Thoroughbred · 30 days

Rev came in ulcer-prone and struggling to hold weight. Thirty days on one pump of Gut X a day, and coat bloom and condition are the visible signs of a gut that’s finally absorbing what it’s fed.

Day 0 Rev on Day 0, off-track, struggling to hold weight

Day 0. Off-track and ulcer-prone, struggling to hold weight.

Day 30 Rev on Day 30, topline and condition restored

Day 30. One pump a day. Topline and condition back.

Daniela’s mare · ~3 months

Through the summer she carried visible ribs and a dropped topline. A few months on Gut X and the weight (and the energy) came back, for around $30 a month.

Before Daniela's mare before, thin with ribs and hip showing

Before. Ribs and hip showing, topline flat.

After Daniela's mare after, filled out and bright

After. Weight back on, coat bright, more energy.

Emily’s mare · Day 1 → Day 30

Shot as a 30-day challenge: same horse, same spot, a month apart. One pump of Gut X a day, and the topline and condition started coming up.

Day 1 Emily's mare on Day 1

Day 1. Starting point: flat topline, dull bloom.

Day 30 Emily's mare on Day 30, topline and condition improved

Day 30. Topline filling, coat coming up.

The absorption gap

What your horse can’t absorb,
your horse can’t use.

Most supplements are powders or pellets. They have to dissolve and survive the gut before any of it counts, and most of it never does. Gut X is liquid and pre-dispersed, so it’s ready the moment it reaches the gut wall.

Liquid Gut X
99%
up to 99% availability
vs
Powders & pellets
2.5%
absorption as low as 2.5%1

Oral bioavailability of administered actives. Powder/pellet figure per Du et al. (2004)1; cited in full above.

With most supplements, you pay for a full dose and your horse absorbs a fraction of it. You’re not getting what you think you’re paying for. With Gut X, what’s on the label is what reaches your horse.

Hyaluronan

Works on contact. Coats and soothes the gut lining the moment it arrives, with no breakdown step to lose along the way.

β-glucan

Binds the gut’s immune receptors directly, supporting a healthy immune response from where it lands.

The physiology

It’s not marketing. Liquid delivery has been the standard in human medicine for decades. Gut X brings it to the barn.

Liquid vs. the rest

Why form is the whole game.

The active ingredients aren’t the differentiator, delivery is. Here’s how liquid stacks up against the dry supplements in most feed rooms.

Gut X · Liquid
Powders
Pellets
Availability
Up to 99%1,2
3–30%3
3–15%4
Goes to work
On contact
Must dissolve first
Needs to break down first
Dose accuracy
One pump, exact
Scoop & settle
Eats around it
Picky-eater approved
Yes
Hit or miss
Hit or miss
Colic coverage
$20,000
It depends
It depends
References
1Goodridge et al. (2011). doi.org/10.1038/nature10071
2Balogh et al. (2008). doi.org/10.1021/jf8017029
3Du et al. (2004). doi.org/10.1002/bdd.392
Ingredients

What’s in the jug, why it’s there, and what the science says.

Every active ingredient in Gut X is at the upper end of its peer-reviewed efficacy range5, 6, 9, 10. No undisclosed dosing. Every gram is named, sourced, and dosed for clinical effect.

The system

Liquid SystemProprietary liquid carrier

The proprietary carrier stabilizes, suspends, and pre-disperses every active before feeding, supporting uniform dosing and up to 99%2, 7, 8 availability, while powders and pellets can assimilate as low as 2.5%1.

up to
99%
availability

Beta Glucanβ-1,3 / 1,6 glucan

β-1,3 / 1,6 glucan, a soluble fiber that works on contact with the gut’s immune tissue, supporting a healthy stomach lining and immune response.2, 4, 10

196
mg / oz

Hyaluronic AcidSodium hyaluronate

A high molecular weight form of hyaluronic acid that works on contact, helping form a hydrated, protective coating across the stomach and small intestine.7, 8, 10, 11

200
mg / oz
References
  1. 1Du, J., White, N., & Eddington, N. D. (2004). Bioavailability of glucosamine and chondroitin sulfate in horses. Biopharmaceutics & Drug Disposition, 25(3), 109–116. doi.org/10.1002/bdd.392
  2. 2Goodridge, H. S., et al. (2011). Dectin-1 activation through beta-glucan immune receptor signaling. Nature, 472, 471–475. doi.org/10.1038/nature10071
  3. 3Goodridge, H. S., et al. (2009). β-glucan recognition by the innate immune system. Immunological Reviews, 230, 38–50. doi.org/10.1111/j.1600-065X.2009.00793.x
  4. 4Tsoni, S. V., & Brown, G. D. (2008). β-glucans and Dectin-1 immune receptor signaling. Annals of the New York Academy of Sciences, 1143, 45–60. doi.org/10.1196/annals.1443.019
  5. 5Picetti, et al. (2021). Oral β-glucan and complement activity in horses. Veterinary World, 14(4), 835–840. doi.org/10.14202/vetworld.2021.835-840
  6. 6Lacerenza, et al. (2024). β-glucan supplementation and LPS-induced endotoxemia in horses. Animals, 14(3), 474. doi.org/10.3390/ani14030474
  7. 7Balogh, L., et al. (2008). Absorption and tissue affinity of high-molecular-weight hyaluronan after oral administration. Journal of Agricultural and Food Chemistry, 56(22), 10582–10593. doi.org/10.1021/jf8017029
  8. 8Sammarco, et al. (2019). Hyaluronan and intestinal mucosal healing. Cells, 8(9), 1074. doi.org/10.3390/cells8091074
  9. 9Slovis, N. M. (2017). Polysaccharide treatment reduces gastric ulceration in active horses. Journal of Equine Veterinary Science, 50, 116–120. doi.org/10.1016/j.jevs.2016.11.011
  10. 10Andrews, et al. (2025). Hyaluronan + β-glucan and gastric ulcer scores in horses. Equine Veterinary Education, 1–10. doi.org/10.1111/eve.70009
  11. 11Misra, S., et al. (2015). Interactions between hyaluronan and its receptors (CD44, RHAMM) regulate inflammation. Frontiers in Immunology, 6, 201. doi.org/10.3389/fimmu.2015.00201
The Protocol

Dr. Peterson’s two-phase protocol

Load for the first 14 days with 2 pumps a day, then settle into a once-daily maintenance pump. Two pumps a day is also recommended for stressful situations, like travel, weather changes, pasture mate changes, and show preparation.

Day 0Day 14Ongoing
Phase 1 ·
Load / Stressful Situations
2 oz / day
Phase 2 · Maintenance 1 oz / day
≈ 3-month supply per gallon
≈ 4-month supply per gallon
How much should I order? Answer 4 questions & we’ll size it for you.
From the barn

112,000 horses. Here are a few of them.

Real members, real horses, real results. Tag #100XEquine to be featured.

Customer photo from Kathryn S.
Customer photo from Julie P.2
Customer photo from Jennie J.4
Customer photo from Naomi R.
Customer photo from Oscar S.
Customer photo from Danielle C.4
Customer photo from Susan P.2
Customer photo from Natalie B.2
Customer photo from Lisa A.
Customer photo from Michelle H.
Customer photo from Odessa A.
Customer photo from Adrienne F.2
Customer photo from Candy M.
Customer photo from Molly A.
Customer photo from Karie M.
Customer photo from Alana C.4
Customer photo from Susan M.2
Customer photo from Erin S.
Customer photo from Janis M.
Customer photo from Jil E.
Customer photo from Billie Jo M.
Customer photo from Christine M.
Customer photo from Becca O.
Customer photo from Tammy R.
Customer photo from Jena T.2
Customer photo from Lyndsay V.
Customer photo from Andrea F.
Customer photo from Victoria D.3
Customer photo from Rebecca J.
Customer photo from S K H.
Customer photo from Kristin C.
Customer photo from Beth R.2
Customer photo from Kendra G.2
Customer photo from Carrie F.5
Customer photo from Payton T.2
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Customer photo from Kyrie R.
Customer photo from Pheraby W.
Customer photo from Heather B.
Dr. Russ Peterson, DVM, Chief Veterinary Officer, 100X Equine
Chief Veterinary Officer

47 years of Equine Medicine, in one jug.

The Veterinary Standard Behind 100X Equine

Dr. Russ Peterson, DVM, MS, DACVSMR, Cert. ISELP brings nearly five decades of equine medicine, sport horse performance, rehabilitation, nutrition, and clinical decision-making to 100X Equine.

As Chief Veterinary Officer, Dr. Peterson helps guide the clinical thinking behind every 100X Equine formula, from ingredient selection to dosing strategy to how those actives are delivered inside the horse.

Gut X reflects that standard: clinically studied beta glucan and hyaluronic acid, transparent dosing, and a proprietary liquid carrier designed to keep the actives stable, dispersed, and ready for biological contact.

Board-certifiedSports Medicine & RehabilitationEquine NutritionFormulation Science
The $20,000 promise

How the Colic Care Coverage works.

Colic surgery can run $5,000–$20,000+. Every active subscription backs your horse with up to $20,000 in surgical reimbursement, so the worst day isn’t also a financial one.

01

Subscribe & enroll

Any active Gut X subscription enrolls your horse in the 100X Colic Care Program, subject to eligibility conditions and a waiting period.

02

Stay covered

Coverage stays active as long as your subscription does. Keep feeding daily gut support, keep the protection in place.

03

Up to $20,000 reimbursed

If your horse needs colic surgery while enrolled, the program reimburses eligible surgical costs up to $20,000.

$20,000Max reimbursement / horse
$0Added cost, included with subscription
Day 45When coverage begins

Colic Care is a reimbursement program, not insurance, and is not a health claim. Eligibility, waiting periods, and terms apply; coverage applies only while a subscription remains active. See full program terms.

$20,000 Colic Care Coverage

Active subscriptions enroll your horse in our program, reimbursing up to $20,000 in colic-surgery costs while coverage stays active.

90-Day Money-Back Guarantee

Feed it daily for 90 days. If you don’t see the difference, we refund you, with free shipping on every order.

Subscribe & Save

Put any protocol on auto-delivery and lock in a better price on every order. Pause, skip, swap, or change your delivery dates anytime, fully in your control.

Still deciding

Questions, answered.

Many owners notice changes within 7–14 days in body condition, appetite, manure quality, and coat shine. Gut X is daily, long-term support, not a quick fix. If you don’t see the difference, you’re backed by our 90-day money-back guarantee.
Gut X is a palatable liquid that coats the existing ration, so most horses accept it with no fuss. If yours is especially fussy, our equine nutritionists help you transition, included free with every order.
Your Gut X subscription is fully flexible. Manage it anytime in your account or by SMS: pause, change delivery dates, or cancel with no fees and no phone tree.
Active subscriptions enroll your horse in the $20,000 Colic Care Coverage Program, reimbursing up to $20,000 in eligible colic-surgery costs while coverage stays active. One-time orders aren’t covered.
The full system

Pair Gut X with another protocol.

Stack more and save up to 40% off. Adjust anytime.

Put your horse on the protocol.

Start with Gut X. Activate up to $20,000 in colic surgery coverage. Built on Dr. Peterson’s 47+ years of equine medicine.

Start with Gut X

Enrollment in the 100X Colic Care Program is required to activate coverage.
See program terms.

Gut X being pumped into a feed scoop in the barn aisle 1 / 4
Gut X · Liquid Delivery

Nutrition starts
in the gut

Powders must break down before the gut can use them. Gut X arrives ready, suspended in a liquid solution, so the gut can use it on contact. One pump a day, top-dressed on feed.

Digestive Support Immune support Body condition & coat Appetite & weight
★★★★★ 4.9 / 5 15,921 reviews 112,000+ horses
Subscribe & Save Save 20% *4 mo. supply
per gallon
One-time purchase One delivery, ships once. *4 mo. supply
per gallon
Free shipping 90-day money-back Pause or cancel anytime

*At the maintenance dose, one 1 oz pump daily.

Your one-time order includes

    *One-time offer for new subscriptions.

    Gut X · 1 Gallon
    Gut X in the arena
    15,921customer reviews★★★★★
    112,000+Horses on product
    $20,000Colic Care
    90-DayMoney-back
    The comparison

    Why form is the whole game.

    The actives are not the differentiator, delivery is. Here is how liquid stacks up against the dry supplements in most feed rooms.

    Gut X liquidPowder / pellet
    Delivery form
    Pre-dispersed liquid, suspendedDry particles, must hydrate
    Availability
    Up to 99%1,2As low as 2.5%3
    Dose consistency
    1 pump = 1 oz, calibratedScoop, settles and separates
    Ready when fed
    On contactMost have a utilization problem
    References
    1 Goodridge et al. (2011). 10.1038/nature10071
    2 Balogh et al. (2008). 10.1021/jf8017029
    3 Du et al. (2004). 10.1002/bdd.392
    Ingredients

    What’s in the jug, and why it’s there.

    Every active is at the upper end of its peer-reviewed efficacy range. No proprietary blends hiding a dose.

    The systemLiquid SystemProprietary liquid carrier 1, 2, 3up to99%availability
    The proprietary carrier stabilizes, suspends and pre-disperses every active before feeding, supporting uniform dosing and up to 99%1,2,3 availability, while powders and pellets can assimilate as low as 2.5%4.
    Beta Glucanβ-1,3 / 1,6 glucan 1, 5, 6196mg / oz
    β-1,3 / 1,6 glucan, a soluble fiber that works on contact with the gut’s immune tissue, supporting a healthy stomach lining and immune response.
    Hyaluronic AcidSodium hyaluronate 2, 3, 6, 7200mg / oz
    A high molecular weight form of hyaluronic acid that works on contact, helping form a hydrated, protective coating across the stomach and small intestine.
    References
    1Goodridge et al. (2011). 10.1038/nature10071
    2Balogh et al. (2008). 10.1021/jf8017029
    3Sammarco et al. (2019). 10.3390/cells8091074
    4Du et al. (2004). 10.1002/bdd.392
    5Tsoni & Brown (2008). 10.1196/annals.1443.019
    6Andrews et al. (2025). 10.1111/eve.70009
    7Misra et al. (2015). 10.3389/fimmu.2015.00201
    8Goodridge et al. (2009). 10.1111/j.1600-065X.2009.00793.x
    9Picetti et al. (2021). 10.14202/vetworld.2021.835-840
    10Lacerenza et al. (2024). 10.3390/ani14030474
    The protocol

    Dr. Peterson’s two-phase protocol

    Load for the first 14 days at two pumps a day, then settle into one pump daily.

    Phase 1 · Load · Day 0 to 14
    2 pumps / day
    ≈ 3-month supply per gallon
    Phase 2 · Maintenance · Ongoing
    1 pump / day
    ≈ 4-month supply per gallon
    1 ounce = 1 pump
    Transformation

    Thirty days, one pump a day.

    Rev

    Off the track, ulcer-prone, and unable to hold condition through a New England winter.

    Day 0Rev on Day 0, struggling to hold weight

    Day 0. Off-track and ulcer-prone, struggling to hold weight.

    Day 30Rev on Day 30, topline and condition restored

    Day 30. One pump a day. Topline and condition back.

    Daniela’s mare

    Came in thin off a hard winter, with ribs and hip showing and a flat topline.

    BeforeDaniela's mare before, thin with ribs and hip showing

    Before. Ribs and hip showing, topline flat.

    AfterDaniela's mare after, filled out and bright

    After. Weight back on, coat bright, more energy.

    Why liquid

    Ready the moment it hits the gut.

    Gut X is delivered in a proprietary liquid form with up to 99% availability1,2. Powders and pellets must first break apart, hydrate and disperse into usable surface area inside a moving gut, a slow, variable process that leaves availability as low as 2.5%3.

    Gut X arrives dispersed, at the correct particle size, suspended and ready on contact, so the gut is not left to solve dispersion problems it was never designed to solve.

    1Goodridge et al. (2011) 2Balogh et al. (2008) 3Du et al. (2004)
    Colic Care Coverage

    Up to $20,000 toward colic surgery.

    Included with every active subscription, at no extra cost. Not insurance you buy, a benefit you keep while you stay on protocol.

    01

    Subscribe

    Your horse is enrolled automatically from the first delivery. No forms, no underwriting, no waiting period beyond the enrollment date.

    02

    Stay on protocol

    Coverage stays active as long as the subscription does. Pause it and coverage pauses with it.

    03

    If the worst happens

    Submit the surgical invoice and we reimburse up to $20,000 of the cost.

    $20,000Maximum reimbursement per covered horse
    $0Additional cost on any subscription

    Program terms, eligibility and exclusions apply. One-time orders are not covered. Read the full terms →

    Who formulates it
    Dr. Russ Peterson, DVM
    Dr. Russ Peterson, DVM
    MS · DACVSMR · Cert. ISELP
    Chief Veterinary Officer

    Nearly five decades of equine medicine, sport horse performance, rehabilitation and nutrition. Gut X reflects that standard: clinically studied beta glucan and hyaluronic acid, transparent dosing, and a liquid carrier built to keep the actives stable and dispersed.

    Still deciding

    Common questions

    How do I dose Gut X?

    One pump per dose, top-dressed on feed. Start with a 14-day loading phase at two pumps a day, then move to one pump for maintenance. The included calibrated pump makes every dose exact. No scooping, no guesswork.

    My horse is a picky eater. Will he take it?

    Gut X is a palatable liquid that coats the existing ration, so most horses accept it with no fuss. If yours is especially fussy, our equine nutritionists help you transition, included free with every order.

    Can I pause, skip or cancel anytime?

    Anytime. Manage everything in your account or by SMS: pause, change delivery dates, or cancel with no fees and no phone tree.

    How does the $20,000 Colic Care Coverage work?

    Active subscriptions enroll your horse in the $20,000 Colic Care Coverage Program, reimbursing up to $20,000 in colic-surgery costs while coverage stays active. One-time orders are not covered.

    Is Gut X legal for competition?

    Yes. USEF and FEI compliant. No prohibited substances, so it is cleared for horses showing under both rule sets.

    How quickly can I expect to see a difference?

    Many horse owners notice visible changes within 7–14 days, especially in body condition, appetite, manure quality, weight and coat shine. Gut X is designed to be fed daily as long-term support, not as a short-term protocol.

    And if you do not see the difference, you are backed by our 90-day money-back guarantee.

    Start the protocol.

    One pump a day. 90-day money-back guarantee. $20,000 Colic Care Coverage on every subscription.

    Subscribe & Save

    Free shipping. Pause, change or cancel anytime.